A deficiency in insulin production or action is the fundamental cause of Diabetes. Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) are dangerous manifestations of diabetes mellitus representing two extremes in the spectrum of uncontrolled diabetic state. Timely diagnosis, comprehensive clinical and biochemical evaluation, and effective management is key to the successful resolution of DKA and HHS. Critical components of the hyperglycemic crises’ management include coordinating fluid resuscitation, insulin therapy, and electrolyte replacement along with the continuous patient monitoring using available laboratory tools to predict the resolution of the hyperglycemic crisis. DKA accounts for 14 percentages of all hospital admissions among diabetics and 16 percentages of all diabetes- related fatalities in India.
Author(s) Details:
Manjiri R. Naik,
Department of Medicine, MGM Medical College and Hospital, Aurangabad, India.
Shamisha Khade,
Department of Medicine, MGM Medical College and Hospital, Aurangabad, India.