Epidemiological Studies have Identified Obesity as an Independent Risk Factor for Atrial Fibrillation : A Part from The Book Chapter : Unraveling the Nexus between Obesity and Atrial Fibrillation: Mechanistic Insights and Clinical Implications

Obesity is undoubtedly among the most critical factors affecting AF. Epidemiological studies have identified obesity as an independent risk factor for atrial fibrillation, but this argument is still controversial. A recent Framingham prospective cohort study suggested that obesity is a risk factor for new-onset AF. Specifically, each 1-unit increase in body mass index (BMI) in men was associated with a 4% increase in AF risk. Compared to normal weight, the risk ratio for overweight people (BMI ≥ 25 kg/m2) is approximately 1.2, and for obese people (defined as BMI ≥ 30 kg/m2), the risk ratio varies from 1.36-2.9, and men are higher than women. Tsang et al. further demonstrated that obesity promotes the progression from paroxysmal to persistent AF. Compared with normal BMI (18.5–24.9 kg/m2), the hazard ratios (HRs) for progression to persistent AF were 1.54 and 1.87 in obese (30–34.9 kg/m2) and severely obese (≥35 kg/m2) patients, respectively. Multiple subsequent studies further supported the potential of obesity to predict new-onset AF and influence the progression from paroxysmal to persistent AF. In the Framingham study, BMI was no longer associated with AF risk after the adjustment for left atrial diameter on echocardiography.

Author(s) Details:

Hongyang Shu,
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Huazhong University of Science and Technology, Wuhan 430000, China.

Jia Cheng,
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Huazhong University of Science and Technology, Wuhan 430000, China.

Na Li,
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Huazhong University of Science and Technology, Wuhan 430000, China.

Zixuan Zhang,
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Huazhong University of Science and Technology, Wuhan 430000, China.

Jiali Nie,
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Huazhong University of Science and Technology, Wuhan 430000, China.

Yizhong Peng,
Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China.

Yan Wang,
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Huazhong University of Science and Technology, Wuhan 430000, China.

Dao Wen Wang,
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Huazhong University of Science and Technology, Wuhan 430000, China.

Ning Zhou,
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China and Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders, Huazhong University of Science and Technology, Wuhan 430000, China.

To Read the Complete Chapter See Here

Related Posts

Gestational Hypertension

The Complications Include Gestational Hypertension : A Part from The Book Chapter : Women and Pregnancies as an Immediate Target against the Obesity Epidemic

The complications include gestational hypertension, preeclampsia, preterm birth, gestational diabetes mellitus (GDM), both, small and large for gestational-age offspring, and a higher prevalence of stillbirth and congenital…

Neuropsychological Scale

The Neuropsychological Scale is the Main Assessment Tool for Cognitive Function : A Part from The Book Chapter : Progress in the Application of Neuropsychological Scales in the Treatment of Schizophrenia

The Neuropsychological Scale is the Main Assessment Tool for Cognitive Function : A Part from The Book Chapter : Progress in the Application of Neuropsychological Scales in…

Adolescence pregnancies

Neonatal Intensive Care Units : A Part from The Book Chapter : Preterm Birth: When is it Too Small to be Born

Adolescence pregnancies bellow the age 18 years are associated with a significant number of premature births and low-birth-weights. There is increased risk of preeclampsia, eclampsia, obstetric cholestasis,…

Fetal Growth

Overweight and Obese Women : A Part from The Book Chapter : Gestational Weight – Smart-phone Calculator: A Case Study of Pregnant Women in India

We observed in our population that women who achieved to have a natural rate of 10% of SGA (small for gestational age) as well as 10% of…

Ministry of Road Transport and Highways

The Number of Road Accidents in 2022 : A Part from The Book Chapter : Epidemiological Study of Road Traffic Accident Cases Admitted in a Tertiary Care Centre of Uttar Pradesh, India: A Hospital Based Cross Sectional Approach

In India, according to ministry of road transport and highways report 2022, a total number of 4,61,312 road accidents have been reported by States and Union Territories…

PBC

Autoimmune Diseases : A Part from The Book Chapter : Association of Systemic Lupus Erythematosus and Primary Biliary Cholangitis

Although patients with an autoimmune disease often present with other autoimmune diseases, several reports have indicated that the incidence of coexisting SLE and PBC ranges from 0%…

Leave a Reply