The isolated compounds from the plant can be used as lead molecules for drug discovery in oral medicine : A Part from The Book : Isolation and Phytochemical Identification of Antibacterial Bioactive Components

The pure compounds obtained from the Moringa oleifera plant have been identified as Quercetin 3-O-β-D-Glucopyranoside, Kaempferol 3-O-β-D-Glucopyranoside, Niazinin-A, and Stigmasterol. These compounds have been found to possess biological activity, particularly in terms of antibacterial properties. The presence of phenolic compounds, especially flavonoids, in the methanolic extract of M. oleifera has been identified as the reason for its antibacterial activity. The isolated compounds from the plant can be used as lead molecules for drug discovery in oral medicine. Additionally, the plant extracts and isolated compounds have been found to be effective against plaque bacteria, making them ideal for synthesizing plant-based biobactericides to reduce the pathogen population. This is particularly important in light of the emerging spread of antimicrobial resistance. In vitro screening has confirmed their antimicrobial activity.

Author(s) Details:

Dr. Koteswara Rao Pagolu,
Department of Biochemistry, Andhra University, Visakhapatnam-53003, Andhra Pradesh, India.

Dr. Vijayakumar Poondla,
Department of Chemistry, Indian Institute of Technology Hyderabad, Kandi, Sangareddy -502284, Telangana, India.

Prof. Raghava Rao Tamanam,
Department of Biochemistry, Andhra University, Visakhapatnam-53003, Andhra Pradesh, India.

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